Associated with deep spirituality and devotion, sapphire is considered to bring peace and contentment to one's soul, as well as trust in the fulfillment of his or her destiny.
Because it evokes the energy of loyalty, honesty, and devotion, the sapphire is often used in the design of engagement rings. 
The most important attribute of the sapphire was said to be the protection against sorcery- it was thought to banish evil spirits and send negative spells back to the sender. Sapphires were once used to guarded off poisonous creatures and kill snakes hiding nearby.
They also provided advanced warning against hidden dangers. As a tool for self improvement, sapphires are a wonderful way to keep your life in check. They are said to have a powerful and transformative gemstone energy that may work quickly and drastically. They will help you connect to the universe, that is, they can open your internal and spiritual self to the powers of the universe.
They are also thought to increase communication with, connection to, and awareness of spirit guides, or angels. They activate and manifest one’s life purpose and focus and karmic agreements for soul growth. Psychologically, the sapphire helps maintain inner peace and are good for one’s mental state. They calm nerves and promote mental clarity, helping with focus and concentration. They have also been used as remedies for mental and nervous disorders.

 

Pearls Historically symbolic of purity, innocence and faith, pearls enhance personal integrity and help clear the mind so that it can be a clean channel for wisdom and spiritual guidance. They were once thought to be the tears of gods.
These Moon and Water ruled "gems" enhance sincerely, truth and loyalty. They bring centering and a calming reflection, as well as attune the wearer to the ebb and flow of life. They are told to give purity, promote faith, charity and integrity, especially personal integrity. Due to its watery and lunar elements, it is quite balancing for the emotions, especially to water signs.

Pearls help one connect with the Goddess, the ultimate feminine energy.
Being that a pearl is created by layer upon layer of substance produced to counteract irritation...it is very nurturing. If used properly, it can lessen stress and it's resulting maladies, such as hypertension, headaches, and exhaustion.

Pearls are said to heal in the area of the Solar Plexus and Sacral Chakras, which would help alleviate symptoms and ailments of the stomach, digestion and ulcers. It is told that Pearl will treat stomach aches, colds, allergies, bronchitis and lung infections.
Chronic headaches as well as migraines may be alleviated or even completely cures when a pearl necklace is worn directly on the skin. Used properly it is said that Pearls will lessen stress ailments such as hypertension and exhaustion which in turn may help to avoid heart attacks and stroke.
Being linked to the Moon, which makes Pearls inherently feminine they are also helpful in the treatment of many female specific ailments, such as aid infertility and easing the discomfort and pain of childbirth.
It is said that drinking pearl water (elixir) regularly over a long period of time will stabilize and balance the production of hormones in ones body.